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Published 2013 Jan 31
The closest structural relative was found to be human CLIC1 (PDB code 1K0O), in which 156 C could be aligned with a root-mean-square deviation (RMSD) value of 0.93 , followed by GSTO1 from Homo sapiens (PDB code 3LFL) (122 aligned C with an RMSD of 2.07 ) and the putative stringent starvation protein A from Burkholderia cenocepacia (PDB code 4QQ7) (122 aligned C with an RMSD of 2.14 ) 12,15
Metformin is absorbed in the small intestine and excreted unchanged by the kidneys, with a plasma half-life of approximately 46 hours
Stability: Liposomes are delicate
Zhao Y, Marotta M, Eichler EE, Eng C, Tanaka H
This matters most if you use diabetes meds, blood pressure meds, blood thinners, transplant meds, or drugs with narrow safety margins
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